Albendazole Bolus 2500mg
Albendazole is anthelmintic yekugadzira inova yeboka rebenzimidazole-derivatives ine chiitiko chinopesana nehupamhi hwehonye uye pamwero wepamusoro wedosi zvakare inopesana nevakuru matanho echiropa.
Pharmacological Action
Albendazole yakasanganiswa ne eelworm's microtubule protein uye inoita basa.Mushure me albenzene yakasanganiswa ne β- tubulin, inogona kudzivirira dimerization pakati pe albenzene ne α tubulin kuungana kuita microtubules.Microtubules ndiwo musimboti chimiro chemasero akawanda.Albendazole's affinity kune nematodes tubulin yakanyanya kukwirira kupfuura kushamwaridzana kwemamalian tubulin, saka chepfu kune mammalian idiki.
Zviratidzo
Prophylaxis uye kurapwa kwehonye mumhuru nemombe senge:
Honye dzeGastrointestinal:Bunostomum, Cooperia, Chabertia, Haemonchus, Nematodirus, Oesophagostomum, Ostertagia, Strongyloides uye Trichostrongylus spp.
Lung worms:Dictyocaulus viviparus uye D. filaria.
Tapeworms:Monieza spp.
Chiropa-fluke:mukuru Fasciola hepatica.
Albendazole inewo ovicidal effect.
Contra-zviratidzo
Administration mumazuva ekutanga e45 ekuberekwa.
Side Effects
Hypersensitivity reactions.
Dosage
Yekutonga nemuromo.
Kune makonye, tapeworms:
Mombe / nyati / bhiza / gwai / mbudzi: 5mg/kg bodyweight
Imbwa / katsi: 10 kusvika 25mg / kg bodyweight
Kune flukes:
Mombe/nyati: 10mg/kg bodyweight
Gwai/mbudzi: 7.5mg/kg bodyweight
Mhuru nemombe: 1 bolus pa 300 kg.uremu hwemuviri.
Kune chiropa-fluke:
1 bolus pa250 kg.uremu hwemuviri.
Yambiro
Chengetedza pasingasvikirwi nevana.
Validation Period
3 years.
Nguva dzekubvisa
- Zvenyama:12 mazuva.
- Zvemukaka :4 mazuva.
Storage
Chengetedza munzvimbo inotonhorera, yakaoma yakachengetedzwa kubva kuchiedza.
Yekushandisa Veterinary Chete, Chengeta kunze kwekusvikirwa nevana
